The development of synthetic biology calls for accurate understanding of the critical functions that allow construction and operation of a living cell. Besides coding for ubiquitous structures, minimal genomes encode a wealth of functions that dissipate energy in an unanticipated way. Analysis of these functions shows that they are meant to manage information under conditions when discrimination of substrates in a noisy background is preferred over a simple recognition process. We show here that many of these functions, including transporters and (...) the ribosome construction machinery, behave as would behave a material implementation of the informationmanaging agent theorized by Maxwell almost 150 years ago and commonly known as Maxwell’s demon (MxD). A core gene set encoding these functions belongs to the minimal genome required to allow the construction of an autonomous cell. These MxDs allow the cell to perform computations in an energy-efficient way that is vastly better than our contemporary computers. (shrink)

A number of experiences have demonstrated how digital solutions are effective in improving quality of life (QoL) and health outcomes for older adults. Smart Health Age-Friendly Environments (SHAFE) is a new concept introduced in Europe since 2017 that combines the concept of Age-Friendly Environments with Information Technologies, supported by health and community care to improve the health and disease management of older adults and during the life-course. This chapter aims to provide an initial overview of the experiences available not only (...) in Europe, based on the research work of the participants of the International Interdisciplinary Network on Health and Well-being in an Age-Friendly Digital World (NET4Age-Friendly), which could be of interest to preventive, health and social authorities. The chapter reports good practices, pain points, and bottlenecks that may require a collaborative, interdisciplinary research approach to facilitate the transformations towards smart, sustainable, health and age-friendly cities and communities. (shrink)

Despite recent essentialist approaches to Kant’s laws of nature, it is unclear whether Kant’s critical philosophy is compatible with core tenets of essentialism. In this paper, I first reconstruct Kant’s position by identifying the key metaphysical and epistemological features of his notion of ‘nature’ or ‘essence’. Two theses about natures can be found in the literature, namely that they are noumenal in character (_noumenal thesis_) and that they guide scientific investigation as regulative ideas of reason (_regulative thesis_). I argue that (...) Kant’s notion of nature does not entail the noumenal thesis and, based on his model of causal explanation, I propose a novel, _phenomenal thesis_, that allows for a better understanding of the function of natures as regulative ideas. In the last part of the paper, I show that Kant’s ‘essentialism’ is a genuine form of essentialism committed to _de re_ modality, although it differs in several respects from major contemporary essentialist accounts. I conclude by suggesting that Kant’s essentialism (if appropriately updated) can be relevant to the contemporary debate, which has so far been dominated by Humean and Aristotelian proposals. (shrink)

Starting from the assumption that aesthetic is an anthropological fact which like language or symbolic thought belongs to the behavioral, cognitive and social register of our species, the article aims to clarify the uses of the category of aesthetic in the human sciences (social anthropology, cognitive psychology, evolutionary anthropology). The epistemological analysis focuses on the implicit assumptions that guide the different methodologies and leads to the elaboration of a conceptual map of the several models of aesthetic adopted in the contemporary (...) debate. Such a result is presented as a preliminary analytical step aimed at fostering an interdisciplinary approach to the complexity and socio-biological diversity of aesthetic phenomena. // Lo estético es un hecho antropológico que —como el lenguaje o el pensamiento simbólico— pertenece al registro comportamental, cognitivo y social de nuestra especie. A partir de esta consideración, el artículo pretende aclarar los usos de la categoría de lo “estético” en las ciencias humanas (antropología social, psicología cognitiva, antropología evolutiva). La investigación epistemológica se concentra en los supuestos implícitos que guían las diferentes metodologías y enfoques teóricos, y finalmente propone un mapa conceptual de los modelos estéticos adoptados en el debate contemporáneo. Este resultado se presenta como un paso analítico preliminar destinado a promover un enfoque interdisciplinario de la complejidad y diversidad sociobiológica de los fenómenos estéticos. (shrink)

In this paper, we propose a methodology to maximize the benefits of interdisciplinary cooperation in AI research groups. Firstly, we build the case for the importance of interdisciplinarity in research groups as the best means to tackle the social implications brought about by AI systems, against the backdrop of the EU Commission proposal for an Artificial Intelligence Act. As we are an interdisciplinary group, we address the multi-faceted implications of the mass-scale diffusion of AI-driven technologies. The result of our exercise (...) lead us to postulate the necessity of a behavioural theory that standardizes the interaction process of interdisciplinary groups. In light of this, we conduct a review of the existing approaches to interdisciplinary research on AI appliances, leading to the development of methodologies like ethics-by-design and value-sensitive design, evaluating their strengths and weaknesses. We then put forth an iterative process theory hinging on a narrative approach consisting of four phases: definition of the hypothesis space, building-up of a common lexicon, scenario-building, interdisciplinary self-assessment. Finally, we identify the most relevant fields of application for such a methodology and discuss possible case studies. (shrink)

A comprehensible model is proposed aimed at an analysis of the reasons for theory change in science. According to model the origins of scientific revolutions lie not in a clash of fundamental theories with facts, but of “old” research traditions with each other, leading to contradictions that can only be eliminated in a more general theory. The model is illustrated with reference to physics in the early 20th century, the three “old” traditions in this case being linked with Maxwellian electrodynamics, (...) Newtonian mechanics and phenomenological thermodynamics. Some modern examples are considered. Key words: Kuhn, Lakatos, Zahar. (shrink)

El artículo tiene como objetivo describir las competencias informacionales a desarrollar durante la formación profesional. Se presenta los referentes teóricos a partir del empleo de un enfoque de sistema que supone el análisis y la síntesis, la inducción y la deducción como métodos de investigación, con el propósito de dar conocer los hitos en las universidades y organizaciones internacionales relacionadas. La modelación fue empleada para la construcción de un nuevo proyecto de desarrollo de competencias informacionales desde la perspectiva de la (...) formación profesional universitaria ajustada a las necesidades de la educación superior en Cuba. El nuevo proyecto se configura en tres unidades básicas (acceso, procesamiento y comunicación), con sus respectivos elementos de competencia, saberes esenciales e indicadores para la evaluación del desempeño. El artículo fundamenta la tesis de que el desarrollo de competencias informacionales debe ser sistemáticamente estructurado, planificado y ejecutado como parte integral de la formación curricular en interacción con los contenidos de las disciplinas docentes, bajo la dirección del profesor y la participación protagónica de los profesionales en formación. -/- ABSTRACT -/- The article aims at describing the competence to be developed during professional training. It presents the theoretical referents by means of an approach system that includes synthesis and analysis, induction and deduction as research methods in order to reveal the milestones of information skills development in universities and related international organizations. Modeling was used for the construction of a new skills development project from the perspective of university professional training according to the needs of Higher Education in Cuba. The new project is composed of three basic units (access, processing and communication), with their respective competence elements, essential knowledge and indicators for the evaluation of the performance. The article supports the theory that information development skills must be systematically structured, planned and implemented as an integral part of the curricular training in interaction with the contents of subjects, under the teacher´s guidance and the active participation of profesionals in training. -/- . (shrink)

In this paper art history and visual studies, the disciplines that study visual culture, are presented as a field whose conjectural paradigm can be used to understand the epistemic problems associated with abduction. In order to do so, significant statements, concepts and arguments from the work of several specialists in this field have been highlighted. Their analysis shows the fruitfulness and potential for understanding the study of visual culture as a field that is interwoven with the assumptions of abductive cognition.

Susan Neiman pointed out to this reviewer the danger that Carl Jung studies pose to contemporary scholars. It is keeping in mind Neiman's cautionary advice that this review establishes Jung's contributions to Romanticism. "[Craig] Stephenson’s analysis of Aurélia has now superseded Arthur Lovejoy’s (1873–1962) and Mario Praz’s (1896–1982) contributions to the definitions of Romanticism.".

Reseña de Lorenzo Peña, Hallazgos filosóficos, Universidad Pontificia de Salamanca, Salamanca, 1992, 363 pp.

Lorenzo Peña y Gonzalo has developed a logic, a legal philosophy and a political thought of a deeply neo-Leibnizian nature. The neo-Leibnizian mark characterizes both his philosophical thesis and the terms has coined in his contributions to the theory of knowledge, theodicy, ontology, political philosophy, etc. Above all, this mark is present in his conception of Law and of the logic of legal situations. Under the light of the political problems and crossroads of the present time, this interview allows (...) for an approach to some of the intellectual findings in his work. (shrink)

O presente artigo pretende mostrar como o filósofo e ensaísta de sobrenome árabe, origem judia e religião católica Fabrice Hadjadj se utiliza de dois autores italianos, a saber, Dante Alighieri e Lorenzo da Ponte, para aprofundar as suas reflexões sobre a noção de Paraíso. No primeiro caso, Hadjadj elabora um encontro entre Dante e Nietzsche, articulando uma compreensão de Paraíso que, na perspectiva hadjadjiana, ultrapassaria as críticas de Friedrich Nietzsche. No segundo, o autor explora o conceito de “redenção”, presente (...) na ópera “Don Giovanni”. Após a exposição da interpretação do filósofo em cada caso, constatamos que a leitura de Dante promove, para Hadjadj, um deslocamento do paraíso do exterior para o interior e que Don Giovanni explicita, segundo Hadjadj, a dinâmica redentora do Paraíso, à medida em que o convite à máxima felicidade não é fruto de uma conquista pessoal ou do cumprimento de um preceito moral, mas um dom que vem do Alto. Finalmente, constatamos o caráter transdisciplinar da leitura que Hadjadj faz de Da Ponte e Dante, considerando-os como autores cujas obras exprimem realidades profundas que precisam ser desveladas e que podem envolver e auxiliar àqueles que leem o texto contemporaneamente. (shrink)

Synthetic biology (SynBio) covers two main areas: application engineering, exemplified by metabolic engi- neering, and the design of life from artificial building blocks. As the general public is often reluctant to embrace synthetic approaches, preferring nature to artifice, its immediate future will depend very much on the public’s reaction to the unmet needs created by the pervasive demands of sustainability. On the other hand, this reluctance should not have a negative impact on research that will now take into account the (...) existence of the multiple transitions that cells face over time. The ages of life—birth, development, maturation, senescence and death—reflect specific key transitions and have, until now, rarely been taken into account in SynBio designs. This results in a mismatch between novelty and the very long evolutionary time that led to the existing chassis [remember that this is the common term used to describe the cellular framework as seen by synthetic biologists (de Lorenzo & Danchin, 2008)]. It also implies that, in general, transitions between growth stages will be taken into account with the appro- priate embodiment of highly specific processes. This is particularly important when adapting new models to their host, whether natural or artificial. Adaptation fol- lows two stages, short-term accommodation of new entities and long-term assimilation into the cell as a whole. This requires discrimination between classes of entities. We suggest that proteins playing the essential role of Maxwell’ demons, here named Maxwell’s dis- criminators (MxDs) to refer to their original function, will permit the assimilation and accommodation of artificial constructs. As a consequence, we can foresee that class discrimination, beyond mere recognition, will be implemented in SynBio 2.0, leading to an authentic par- adigm shift (Kuhn, 1996), based on conceptions that embody information as a genuine currency of reality. (shrink)

ABSTRACTThe question of how common usage could be constitutive for the meaning of linguistic expressions has been discussed by Renaissance philosophers such as Lorenzo Valla, and it also played an important role in Renaissance theories of juridical interpretation. An aspect of the analysis of common usage in Renaissance theories of juridical interpretation that concerns the role of presumption has not yet found much attention. Renaissance jurists such as Simone de Praetis, Nicolaus Everardus, and Aimone de Cravetta saw that both (...) the usage of Latin by practitioners of law and the vernacular common usage of ordinary people often differed from the technical definition of legal concepts as laid down by ancient jurists or modern legislators. In some cases, they ascribed both to Latin and to vernacular common usage the power of changing the meaning of juridical terms. Still, they were aware of the fact that matters of common usage involve always a degree of uncertainty. The methodological notion of presumption is one of the concepts that figured most prominently in Renaissance approaches to the problem of uncertainty, and, in particular, it was applied in the analysis of meaning-change of legal concepts through common usage. (shrink)

This paper attempts a reconstruction of reason’s contribution to empirical truth in connection with Kant’s definition of truth as the agreement of cognition with its object. I argue that Kant’s treatment of truth in the Transcendental Analytic gets completed in the Appendix to the Transcendental Dialectic with an often neglected but compelling argument (what I shall call the Variety Argument). This argument postulates such a variety in the appearances as to undermine any attempt at formulating empirical truths. Crucially, I argue (...) that this variety does not depict an extreme-case scenario, but our own epistemic situation without reason. Reason completes Kant’s theory of truth by allowing the understanding (i.) to form empirical concepts and (ii.) approximate to empirical truth. (shrink)

Why is there something rather than nothing? About this storied question we challenge the commonly accepted main assumption: the existence of something. Starting from Nothing only, we explain how our perceived reality emerges as an illusory self-referential interpretation of Nothing and build a framework to give precise definitions to fundamental concepts such as existence, reality, nothingness and somethingness. We then explore the consequences of this framework and we discover an explanation for the existence of laws of physics in our illusory (...) reality. By aiming to describe reality starting with Nothing, we provide the first instance of an assumption-less theory. (shrink)

In this paper, we embark on the complicated discussion about the nature of vice in Virtue Ethics through a twofold approach: first, by taking seriously the claim that virtues (and certain flavours of vices) are genuinely dispositional features possessed by agents, and secondly, by employing a pluralistic attitude borrowed from Battaly’s pluralism (2008). Through these lenses, we identify three varieties of viciousness: incontinence, indifference, and malevolence. The upshot is that the notion of vice is not as categorically homogeneous as that (...) of virtue: some states of viciousness consist in interference of present virtuous dispositions, or mimicking of absent vicious ones, whereas others can be considered genuine dispositions themselves. Furthermore, this set-up can provide an interesting, albeit highly idealized story as to how, through the interference in one’s environment, one gets acquainted with vice in various degrees. Finally, this approach can be illuminating vis-à-vis Virtue Ethics in general; e.g. we can employ it to discuss more productively Johnston’s (2003) objection to Hursthouse’s (1999) account of moral conduct. Finally, this approach can be illuminating vis-a-vis Virtue Ethics in general; e.g. we can employ it to discuss more productively Johnston’s (2003) objection to Hursthouse’s (1999) account of moral conduct. (shrink)

In this paper, I offer a systematic account of Kant’s view on ‘phenomenal substance’. Several studies have recently analysed Kant’s notion of substance. However, I submit that more needs to be said about how this notion is reconceptualized within the critical framework to vindicate a genuine and legitimate sense of substance in the phenomenal realm. More specifically, I show that Kant’s transcendental idealism does not commit him to a rejection of substantiality in phenomena. Rather, Kant isolates a general notion of (...) substance (as ultimate subject) and argues that (i) the relationality of phenomena is compatible with this notion; and that (ii) matter and all its parts are the ultimate subjects of everything existing in space (as what is independently movable in space). I suggest that vindicating a genuine and legitimate notion of phenomenal substance has far-ranging consequences for the interpretation of Kant’s empirical realism. (shrink)

What can we know? We know many things about the world around us: whether it is raining outside, the result of last night’s game, or how vaccines work. But we also want to know more. For example, we may want to know the ultimate origin of the universe, whether God exists, or whether there are such things as souls. Philosophers have long asked this type of questions — questions that concern a kind of knowledge that goes beyond our experience. A (...) wide range of answers (often contradicting each other) have been endlessly debated. Dissatisfied with this state of inquiry, Kant proposes a revolution in philosophy, which does not consist in devising new answers to these questions, but rather in analyzing our own capacity for knowledge. Such an analysis aims to shed light on the limits of our cognitive faculties and to reveal their true potential. In this article, we will see how Kant’s philosophy offers a revolutionary approach to our deep thirst for knowledge. (shrink)

Scientific models typically contain idealizations, or assumptions that are known not to be true. Philosophers have long questioned the nature of idealizations: Are they heuristic tools that will be abandoned? Or rather fictional representations of reality? And how can we reconcile them with realism about knowledge of nature? Immanuel Kant developed an account of scientific investigation that can inspire a new approach to the contemporary debate. Kant argued that scientific investigation is possible only if guided by ideal assumptions—what he calls (...) “regulative ideas”. These ideas are not true of objects of nature, and yet they are not heuristic tools or fictional represen- tations. They are necessary rules governing the construction and assessment of scientific explanations. In this paper, I suggest that some idealizations can be interpreted as having necessary regulative value and as being compatible with scientific realism. I first analyze the puzzle of the nature of idealization and present the main approaches to this topic in the literature. Second, I reconsider the puzzle vis-a-vis a restricted, Kantian definition of idealization and a novel characterization of the relation between idealization and truth. Finally, I discuss in detail an example of idealization (the Hardy-Weinberg equilibrium) along the suggested Kantian lines. (shrink)

According to the most common interpretation of the simulation argument, we are very likely to live in an ancestor simulation. It is interesting to ask if some families of simulations are more likely than others inside the space of all simulations. We argue that a natural probability measure is given by computational complexity: easier simulations are more likely to be run. Remarkably this allows us to extract experimental predictions from the fact that we live in a simulation. For instance we (...) show that it is very likely that humanity will not achieve interstellar travel and that humanity will not meet other intelligent species in the universe, in turn explaining the Fermi's Paradox. On the opposite side, experimental falsification of any of these predictions would constitute evidence against our reality being a simulation. (shrink)

I consider a problem for functional reductionism, based on the following tension. Say that b is functionally reduced to a. On the one hand, a and b turn out to be identical, and identity is a symmetric relation. On the other hand, functional reductionism implies that a and b are asymmetrically related: if b is functionally reduced to a, then a is not functionally reduced to b. Thus, we ask: how can a and b be asymmetrically related if they are (...) the same thing? I propose a solution to this tension, by distinguishing between ontological levels and levels of description. (shrink)

A growing body of research has examined how people judge the persistence of identity over time—that is, how they decide that a particular individual is the same entity from one time to the next. While a great deal of progress has been made in understanding the types of features that people typically consider when making such judgments, to date, existing work has not explored how these judgments may be shaped by normative considerations. The present studies demonstrate that normative beliefs do (...) appear to play an important role in people's beliefs about persistence. Specifically, people are more likely to judge that the identity of a given entity remains the same when its features improve than when its features deteriorate. Study 1 provides a basic demonstration of this effect. Study 2 shows that this effect is moderated by individual differences in normative beliefs. Study 3 examines the underlying mechanism, which is the belief that, in general, various entities are essentially good. Study 4 directly manipulates beliefs about essence to show that the positivity bias regarding essences is causally responsible for the effect. (shrink)

In this paper, we focus on the moral responsibility of organized groups in light of historicism. Historicism is the view that any morally responsible agent must satisfy certain historical conditions, such as not having been manipulated. We set out four examples involving morally responsible organized groups that pose problems for existing accounts of historicism. We then pose a trilemma: one can reject group responsibility, reject historicism, or revise historicism. We pursue the third option. We formulate a Manipulation Condition and a (...) Guarding Condition as addendums to historicism that are necessary to accommodate our cases of group responsibility. (shrink)

Graham Priest's book In Contradiction is a bold defense of the existence of true contradictions. Although Priest's case is impressive, and many of his arguments are correct, his approach is not the only one allowing for true contradictions. As against Priest's, there is at least one contradictorialist approach which establishes a link between true contradictions and degrees of truth. All in all, such an alternative is more conservative, closer to mainstream analytical philosophy. The two approaches differ as regards the floodgate (...) problem. Priest espouses a confinement policy banning contradictions except in a few special domains, particularly those of pure semantics and set-theory , whereas the alternative approach admits two negations -- natural or weak negation and strong negation, the latter being classical; accordingly, the alternative approach prohibits any contradiction involving strong negation, thus providing a syntactic test of what contradictions have to be rejected. (shrink)

During the first half of the twentieth century, many philosophers of memory opposed the postulation of memory traces based on the claim that a satisfactory account of remembering need not include references to causal processes involved in recollection. However, in 1966, an influential paper by Martin and Deutscher showed that causal claims are indeed necessary for a proper account of remembering. This, however, did not settle the issue, as in 1977 Malcolm argued that even if one were to buy Martin (...) and Deutscher’s argument for causal claims, we still don’t need to postulate the existence of memory traces. This paper reconstructs the dialectic between realists and anti-realists about memory traces, suggesting that ultimately realists’ arguments amount to inferences to the best explanation. I then argue that Malcolm’s anti-realist strategy consists in the suggestion that causal explanations that do not invoke memory traces are at least as good as those that do. But then, Malcolm, I argue that there are a large number of memory phenomena for which explanations that do not postulate the existence of memory traces are definitively worse than explanations that do postulate them. Next, I offer a causal model based on an interventionist framework to illustrate when memory traces can help to explain memory phenomena and proceed to substantiate the model with details coming from extant findings in the neuroscience of memory. (shrink)

Philosophers have debated at length the epistemological status of scientific thought experiments. I contend that the literature on this topic still lacks a common conceptual framework, a lacuna that produces radical disagreement among the participants in this debate. To remedy this problem, I suggest focusing on the distinction between the internal and the external validity of an experiment, which is also crucial for thought experiments. I then develop an account of both kinds of validity in the context of thought experiments. (...) I show that we can naturally conceptualise internal validity in terms of games of make-believe. Then, I argue that external validity is best defined as accurate representation of a target system. Finally, I turn back to the current debate on thought experiments and show that my diarchic account provides a general framework that can be shared by the competing philosophical views, as well as a fruitful guide for their reconciliation. (shrink)

Spontaneous collapse theories of quantum mechanics turn the usual Schrödinger equation into a stochastic dynamical law. In particular, in this paper, I will focus on the GRW theory. Two philosophical issues that can be raised about GRW concern (i) the ontology of the theory, in particular the nature of the wave function and its role within the theory, and (ii) the interpretation of the objective probabilities involved in the dynamics of the theory. During the last years, it has been claimed (...) that we can take advantage of dispositional properties in order to develop an ontology for GRW theory, and also in order to ground the objective probabilities which are postulated by it. However, in this paper, I will argue that the dispositional interpretations which have been discussed in the literature so far are either flawed or – at best – incomplete. If we want to endorse a dispositional interpretation of GRW theory we thus need an extended account that specifies the precise nature of those properties and which makes also clear how they can correctly ground all the probabilities postulated by the theory. Thus, after having introduced several different kinds of probabilistic dispositions, I will try to fill the gap in the literature by proposing a novel and complete dispositional account of GRW, based on what I call spontaneous weighted multi-track propensities. I claim that such an account can satisfy both of our desiderata. (shrink)

Lam and Esfeld have argued that, within Bohmian mechanics, the wave function can be interpreted as a physical structure instantiated by the fundamental particles posited by the theory. Further, to characterize the nature of this structure, they appeal to the framework of Ontic Structural Realism, thereby proposing a structuralist interpretation of Bohmian mechanics. However, I shall point out that OSR denotes a family of distinct views, each of which maintains a different account about the relation between structures and objects, and (...) entails a different kind of ontology. Thus, in this paper I will show how to articulate the structuralist approach to Bohmian Mechanics accordingly to the different standard versions of OSR, and I will evaluate these alternatives. Moreover, I will propose a novel and _sui generis_ kind of structuralist interpretation of Bohmian Mechanics, based on the framework of metaphysical coherentism. (shrink)

Current theories of the division of cognitive labor are confined to the “context of justification,” assuming exogenous theories. But new theories are made from the same labor that is used for developing existing theories, and if none of this labor is ever allocated to create new alternatives, then scientific progress is impossible. A unified model is proposed in which theories are no longer given but a function of the division of labor in the model itself. The interactions of individuals balancing (...) the exploitation of existing theories and the exploration of new theories results in a robust cyclical pattern. (shrink)

I highlight three features of P.F. Strawson’s later, neglected work on freedom and responsibility. First, in response to a criticism by Rajendra Prasad, Strawson explicitly rejects an argument put forward in ‘Freedom and Resentment’ against the relevance of determinism to moral responsibility. Second, his remarkable acceptance of Prasad’s criticism motivates him to take the ‘straight path’, that is, to be straightforward about the relation between determinism, freedom, the ability to do otherwise and the conditions of responsibility. He claims that the (...) ability to do otherwise is a necessary condition of responsibility and provides a list of additional conditions, including a knowledge condition. Third, he clarifies the relation between responsibility, quality of will and the reactive attitudes. The latter do not figure essentially in his answer to the question, ‘What are the conditions of responsibility?’, but they do play an essential role in his answer to the question, ‘Why do we have the concept of responsibility?’ We have it, Strawson suggests, because of our natural concern about the quality of will with which people act, a concern expressed in our reactive attitudes. I argue that, although Strawson’s later work definitely involves a shift of emphasis when compared to ‘Freedom and Resentment’, his overall account of freedom and responsibility is coherent. The later work helps to better understand the nature and significance of Strawson’s contribution, and to identify problems with common interpretations of and objections to ‘Freedom and Resentment’. (shrink)

Scholarship on Plato's Timaeus has paid relatively little attention to Tim. 77a–81, a seemingly disjointed passage on topics including plants, respiration, blood circulation, and musical sounds. Despite this comparative neglect, commentators both ancient and modern have levelled a number of serious charges against Timaeus' remarks in the passage, questioning the coherence and explanatory power of what they take to be a theory of respiration. In this paper, I argue that the project of 77a–81e is not to sketch theories of respiration, (...) circulation, and digestion, but to explain how the human body is maintained in light of and despite constant environmental depletion. Further, I argue that in order to understand this account of “the replenishing system,” we need to understand Timaeus' striking analogy of the fish trap or nassa. Commentators have generally focused directly on the workings of the bodily construction that Timaeus likens to a fish trap, but without considering how we should understand the analogy qua analogy. I develop a functional reading of the analogy that yields a coherent account of the replenishing system on which previous criticisms of Timaeus' remarks on respiration do not arise. Aside from lending greater unity to the passage, both internally and within its immediate context in the dialogue, this account of the replenishing system contributes to our understanding of Timaeus' reason-and-necessity explanatory framework as applied to the human body and has noteworthy implications for specific explanatory principles, in particular like-to-like motion and circular thrust. (shrink)

As one would expect, Kant believes that there is a tension, and even a conflict, between our bodily humanity and its ethical counterpart: ‘Inclination to pleasurable living and inclination to virtue are in conflict with each other’ (Anthropology, 185-86 [7:277]). What is more unexpected, however, is that he further claims that this tension can be resolved in what he calls an example of ‘civilised bliss’, namely dinner parties. Dinner parties are, for Kant, part of the ‘highest ethicophysical good’, the ultimate (...) resolution of the conflict between our physical body and our moral powers, which consists in finding the right proportions for the ‘mixture’ between our partly ‘sensuous’ and partly ‘ethicointellectual’ nature. The aim of this paper is not only to explain Kant’s account of the ideal proportions of ethicophysical good in dinner parties, but also, and more importantly, to argue that dinner parties are in fact the ultimate experience for us, human beings. (shrink)

Functionalism is the view that being x is to play the role of x. This paper defends a functionalist account of three-dimensional entities in the context of Wave Function Realism (WFR), that can explain in detail how we can recover three-dimensional entities out of the wavefunction. In particular, the essay advocates for a novel version of WFR in terms of a functional reductionist approach in the style of David Lewis. This account entails reduction of the upper entities to the bottom (...) ones, when the latter behave appropriately. As applied to WFR, it shows how the wavefunction can turn out to be identical to three-dimensional objects, provided certain conditions. The first major goal of the paper is thus to put forward an improved and more rigorous version of WFR, which dissolves several extant issues about the theory, and can serve as a starting point for future literature on the topic. Moreover, the second major goal of the article is to take WFR as a case study to demonstrate the pros of functional reductionism, especially in the form defended here, thereby helping to bring this view back in the philosophy of science debate. The positive upshots of this paper suggest a possible application of functional reductionism also to other contexts. (shrink)

Strawsonians about moral responsibility often claim that our practices of holding morally responsible fix the facts of moral responsibility, rather than the other way round. Many have argued that such ‘reversal’ claims have an unwelcome consequence: If our practices of holding morally responsible fix the facts of moral responsibility, does this not imply, absurdly, that if we held severely mentally ill people responsible, they would be responsible? We provide a new Strawsonian answer to this question, and we explore the relation (...) between reversal claims and (in)compatibilism. (shrink)

Functional reductionism characterises inter-theoretic reduction as the recovery of the upper-level behaviour described by the reduced theory in terms of the lower-level reducing theory. For instance, finding a statistical mechanical realiser that plays the functional role of thermodynamic entropy allows for establishing a reductive link between thermodynamics and statistical mechanics. This view constitutes a unique approach to reduction that enjoys a number of positive features, but has received limited attention in the philosophy of science. -/- This paper aims to clarify (...) the meaning of functional reductionism in science, with a focus on physics, to define both its place with respect to other approaches to reduction and its connection to ontology. To do so, we develop and explore two alternative frameworks for functional reduction, called Syntactic Functional Reductionism and Semantic Functional Reductionism. They represent two different possible stances on the view that expand and improve the basic functional reductionist approach along different lines, and make clear how the approach works in practice. The former elaborates on David Lewis’ account, is connected with the syntactic view of theories, is committed to a logical characterisation of functional roles, and is embedded within Nagelian reductionism. The latter adopts a semantic view of theories, spells out functional roles mainly in terms of mathematical roles within the models of theories, and is expressed in terms of the related structuralist approach to reduction. The development of these frameworks has the final goal of advancing functional reductionism, to make it a fully-fledged alternative account for reduction in science. (shrink)

Cloud computing is rapidly gaining traction in business. It offers businesses online services on demand (such as Gmail, iCloud and Salesforce) and allows them to cut costs on hardware and IT support. This is the first paper in business ethics dealing with this new technology. It analyzes the informational duties of hosting companies that own and operate cloud computing datacenters (e.g., Amazon). It considers the cloud services providers leasing ‘space in the cloud’ from hosting companies (e.g, Dropbox, Salesforce). And it (...) examines the business and private ‘clouders’ using these services. The first part of the paper argues that hosting companies, services providers and clouders have mutual informational (epistemic) obligations to provide and seek information about relevant issues such as consumer privacy, reliability of services, data mining and data ownership. The concept of interlucency is developed as an epistemic virtue governing ethically effective communication. The second part considers potential forms of government restrictions on or proscriptions against the development and use of cloud computing technology. Referring to the concept of technology neutrality, it argues that interference with hosting companies and cloud services providers is hardly ever necessary or justified. It is argued, too, however, that businesses using cloud services (banks, law firms, hospitals etc. storing client data in the cloud, e.g.) will have to follow rather more stringent regulations. (shrink)

A common style of argument in the literature on free will and moral responsibility is the Manipulation Argument. These tend to begin with a case of an agent in a deterministic universe who is manipulated, say, via brain surgery, into performing some action. Intuitively, this agent is not responsible for that action. Yet, since there is no relevant difference, with respect to whether an agent is responsible, between the manipulated agent and a typical agent in a deterministic universe, responsibility is (...) not compatible with the truth of determinism. In response, some theorists have argued that there is a relevant difference, and have developed two sorts of accounts of that difference: bypassing views, and manipulator-focused views. Manipulator-focused views suggest that the difference concerns the presence of a manipulator, whereas bypassing views suggest that the relevant difference concerns the fact that the action issues from attitudes that the manipulated agent acquired in a way that bypassed her capacities for control over her mental life. One sort of case used to decide between these sorts of accounts is a case of machine induction, which is just like a manipulation case, yet the change in the agent is the result of some natural force. Against the received view, Xiaofei Liu argues that such cases pose problems for bypassing views, and favor manipulator-focused views instead. This paper addresses Liu’s arguments, as well as a variety of cases, concluding that cases of machine induction do not provide motivation for a bypassing theorist to adopt a manipulator-focused view. (shrink)

In this paper I claim that perceptual discriminatory skills rely on a suitable type of environment as an enabling condition for their exercise. This is because of the constitutive connection between environment and perceptual discriminatory skills, inasmuch as such connection is construed from an ecological approach. The exercise of a discriminatory skill yields knowledge of affordances of objects, properties, or events in the surrounding environment. This is practical knowledge in the first-person perspective. An organism learns to perceive an object by (...) becoming sensitized to its affordances. I call this position ecological disjunctivism. A corollary of this position is that a case of perception and its corresponding case of hallucination—which is similar to the former only in some respects—are different in nature. I show then how the distinguishability problem is addressed by ecological disjunctivism. (shrink)

Proponents of moral enhancement believe that we should pursue and apply biotechnological means to morally enhance human beings, as failing to do so is likely to lead to humanity's demise. Unsurprisingly, these proposals have generated a substantial amount of debate about the moral permissibility of using such interventions. Here I put aside concerns about the permissibility of moral enhancement and focus on the conceptual and evidentiary grounds for the moral enhancement project. I argue that such grounds are quite precarious.

A new reprogenetic technology, mitochondrial replacement, is making its appearance and, unsurprisingly given its promise to wash off our earthly stains --or at least the scourges of sexual reproduction--, John Harris finds only reasons to celebrate this new scientific feat.1 In fact, he finds mitochondrial replacement techniques (MRTs) so “unreservedly welcome” that he believes those who reject them suffer from “a large degree of desperation and not a little callousness.”2 Believing myself to be neither desperate nor callous, but finding myself (...) also no closer at all – not even after reading his article—to following Harris in welcoming these technologies wholeheartedly, it seems appropriate to respond. (shrink)

In “Correspondence to Reality in Ethics”, Mario Brandhorst examines the view of ethics that Wittgenstein took in his later years. According to Brandhorst, Wittgenstein leaves room for truth and falsity, facts, correspondence and reality in ethics. Wittgenstein's target, argues Brandhorst, is objectivity. I argue that Brandhorst's arguments in favour of truth, facts, reality and correspondence in ethics invite similar arguments in favour of objectivity, that Brandhorst does not recognise this because his conception of objectivity is distorted by a Platonist picture (...) and that he misinterprets the passage which he takes to support a Wittgensteinian case against objectivity. (shrink)

Since Saul Kripke’s influential work in the 1970s, the revisionary approach to semantic paradox—the idea that semantic paradoxes must be solved by weakening classical logic—has been increasingly popular. In this paper, we present a new revenge argument to the effect that the main revisionary approaches breed new paradoxes that they are unable to block.

Can an identity be the proper subject of an explanation? A popular stance, albeit not one often argued for, gives a negative answer to this question. Building from a contentious passage from Jaegwon Kim in this direction, we reconstruct an argument to the conclusion that identities, to the extent in which they are necessary, cannot be explained. The notion of contrastive explanation, characterized as difference-seeking, will be crucial for this argument; however, we will eventually find the argument to be unsatisfactory. (...) On the contrary, the discussion provides enough resource to sketch a very simple framework for a non-causal contrastive explanation of identities. Many instances will be provided, with different varieties of explanans, ultimately suggesting that certain entailment or biconditional principles involving identities (first and foremost, so-called two-level identity criteria) may indeed be taken to have an inherent explanatory value. (shrink)

This paper promotes an evolutionary emergent panpsychism that has several advantages over the popular constitutive type. It recognizes layers in nature and theorizes an intelligible stepwise evolution of consciousness from the micro to the macro level. It is consistent with mental causal efficacy at the higher animal level and not just base particle levels. Finally it can explain to some degree the sense we have of a diachronic self persisting in time.

There are various forms of teleological thinking central to debates in the early modern and modern periods, debates in which David Hume (1711–1776) is a key figure. In the first section, we shall introduce three levels at which teleological considerations have been incorporated into philosophical accounts of man and nature, and sketch Hume’s criticisms of these approaches. In the second section, we turn to Hume’s non-teleological ‘science of man’. In the third section, we show how Hume has an account of (...) human flourishing that is not dependent on teleology. In the fourth section, we shall speculate as to the relation between Hume’s account of human nature and contemporary evolutionary accounts of morality and reasoning. (shrink)